منابع مشابه
Microparticles in angiogenesis: therapeutic potential.
Considered during the past decades as cell dust, microparticles are now deemed true biomarkers and vectors of biological information between cells. Depending on their origin, the composition of microparticles varies and the subsequent message transported by them, such as proteins, mRNA, or miRNA, can differ. Recent studies have described microparticles as "cargos" of deleterious information in ...
متن کاملRole of Membrane Microparticles in Angiogenesis
Hedgehog (Hh) proteins belong to a class of morphogens involved in many biological processes during embry-onic development; they are relatively silent during normal adult life although they may be recruited postnatally in re-sponse to tissue injury. Three secreted proteins have been identified: Sonic hedgehog (Shh), Desert hedgehog and Indianhedgehog. The interaction of Hh ligand wi...
متن کاملDying for attention: microparticles and angiogenesis.
Microparticles, which were initially described as cell dust, have revealed over the past few years several exciting and unexpected properties. Microparticles are submicron vesicles shed from plasma membranes following cell activation or apoptosis, whose protein and lipid profile may be considered as a snapshot of the phenotype of the cell they stem from. The molecular mechanisms of microparticl...
متن کاملEndothelial microparticles affect angiogenesis in vitro: role of oxidative stress.
Endothelium-derived microparticles have recently been described as a new marker of endothelial cell dysfunction. Increased levels of circulating microparticles have been documented in inflammatory disorders, diabetes mellitus, and many cardiovascular diseases. Perturbations of angiogenesis play an important role in the pathogenesis of these disorders. We demonstrated previously that isolated en...
متن کاملMicroparticles in Angiogenesis: Therapeutic Potential Formation, Fate, and Function of Platelet Microparticles Microparticles in Vascular Function and Atherothrombosis Leukocyte-Derived Microparticles in Vascular Homeostasis
Considered during the past decades as cell dust, microparticles are now deemed true biomarkers and vectors of biological information between cells. Depending on their origin, the composition of microparticles varies and the subsequent message transported by them, such as proteins, mRNA, or miRNA, can differ. Recent studies have described microparticles as “cargos” of deleterious information in ...
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ژورنال
عنوان ژورنال: Circulation Research
سال: 2011
ISSN: 0009-7330,1524-4571
DOI: 10.1161/circresaha.110.233049